Khyungpo Tsultrim Goon was born to father Ponpo Gone and mother Chemo Kinden in the female firebird year. His parents wanted him to become the head of their household since he was the first-born Son. Tsultrim Gon wanted to follow the path of Dharma and escaped from his home by taking the supplies of his brother who was supposed to become a monk. Tsultrim Gon met Lama Shangtonpa who became his spiritual guide and gave him the name Khyungpo Tsultrim Gon and granted him the empowerments of Six Yoga's of Niguma, and the complete instructions for each of the Six Yoga's and many other teachings.
Tsultrim Gon took his monastic vows from the abbot Gendun Gyamtso of Jonang. He went to meet the lord Rangjung Dorje at Tsurpu. He also met Rolpe Dorje the incarnation of lord Rangjung Dorje and received empowerments and numerous teachings. Tsultrim Gon then took full ordination from Lama Zhonnu Jangchub, abbot to Gendun Gangway. Tsultrim Gon remained in the area of Upper Shang for twenty-five years meditating and giving instructions to the people who were suffering from diseases and demons and had many great visions of his Lamas and Deities. Khyungpo Tsultrim Gon passed away in the tiger year with rains of flowers and rainbows filling and illuminating space. From his cremation fire the sound of, Om Hri Ha Ha Hung Hung Phet could be herd. When his cremation Shrine was opened many sacred relics were discovered and distributed to his disciples.